CASE STUDIES

Cosmetics: research project on product usability

Development of an algorithm to predict “hand positions” during a make-up activity, with sensor data

Construction of a “beta” learning algorithm with a neural network on a set of “fake” hand positions
Construction of a similar algorithm to predict real make-up hand positions

Prediction tool assessing the probabilities of hand position on the basis of input data

Petroleum : study of the performance of new products

Study of fuel properties on the performance and wear of car engines

Experimental design set-ups to limit the number of tests
Statistical modelling of the different study answers anticipated, using PLS models
Estimation of the effect of the different fuels and study of the variability induced in engine performance

Study report assessing the impacts of fuel properties and specifying the optimal product composition to respond to the client’s challenges, under their constraints, and delivering the best performance

Pharmaceutical laboratory: meta-analysis consolidating 15 years of clinical studies

Standardization of 42 databases from clinical studies conducted over a period of 15 years and meta-analysis of these data

CDISC conversion of heterogeneous databases from 42 clinical studies
SAS programming, safety and immunogenicity analysis
Statistical report including raw and synthetic tables

CDISC databases
Study report

Telecoms: evaluation of the performance of a new contract subscription process

Field study to assess the impact of a new customer pathway under real-life conditions of in-store subscription

Design of a tablet app to monitor and record the customer pathway and the time required for specific actions/steps
Management of the field study in 10 stores in France over a 2-week period (recruitment, training, team management)
Data merge, data management and data analysis

Study report assessing the time and financial benefits provided by the new process (employee performance, expected financial impact with national roll-out)

Food processing industry : study of a product line and remediation of defects

Study of impact parameters on a production line and assessment of their consequences on the finished product as part of a continuous improvement project

Management of a DMAIC project to map the process, define the production variables, and the expected gold standard
Analysis of production data and construction of a statistical model “explaining” product parameters with the production variables
Assessment of the impacts, definition of the real gold standard, and management of the “improvement” and “check” steps of the DMAIC

Study report defining the impact of the production parameters on the finished product and its quality
Definition of further steps to improve the industrial process

Food marketing: market study of product placement strategy for different countries

Establish the nutritional/sensory placement of a dairy product against its competitors and according to the consumption preferences of different countries

Data mining and multivariate analysis of nutritional and sensory surveys
Characterization of sensory preferences among population clusters

Study report defining consumer profiles in the target markets

Pharmaceutical laboratory: statistical activities in -Omics projects

Obtain support to define study methodologies for and analyze data from various -Omics projects

Definition of statistical methodologies adapted to clinical designs and study objectives
Exploratory analysis to identify prognostic biomarkers
Analysis of different types of data (transcriptomics, RNAseq, qPCR, etc.) to achieve various objectives

Statistical methodologies
Analysis algorithms
Study reports

Medical device: improvement of analytical methods

Devise and lead a training session for industrial teams, and coach them in their everyday data analyses

Study of analytical routines/habits and the statistical needs of field teams
Design of a tailor-made program and training session
Consulting on methodologies, review, or to perform specific analyses (SPC, control charts, sampling, etc.)

Training document
“Hotline” support to confirm choices and analyses
Consultancy and study reports

Cosmetics: describe the diversity of skin microbiota

Set a score for microbiota diversity, identify biomarkers correlated with skin biodiversity and compare the impact of different products on this biodiversity according to the subject’s origins.

Construction of diversity scores
Correlation studies between biological parameters and diversity scores
Subject classification
Description and comparison of different products

Diversity score calculation method
Statistical report assessing the differences between skin zones and populations

Medical network specialized in cardiology: study of the change in the use of anticoagulant treatment and comparison of mortality between 2 registers from 2003 and 2017

Comparison of 2 registers, 15 years apart. Use of “propensity score matching” (PSM) methodology

Determination of prognostic factors for PSM
Reduction of the population to compare these registers using PSM
Multivariate analysis presenting predictors of anticoagulant intake
Evaluate mortality between these 2 registers

Statistical analysis plan
Study report

Veterinary laboratory: conversion and improvement of a VBA macro in SAS programs

Conversion of a VBA macro into an SAS macro and implementation of new functionality to bring flexibility to statistical analyses, and application to a first study database

Data management for the study and database cleaning
Conversion of the VBA macro into SAS
Descriptive analysis
Creation of a statistical model (ANOVA and ANCOVA) to analyze the effect of treatment

SAS program/macro
Statistical report